Background: Various strategies have been proposed to minimize reperfusion delay in patients who are candidate for primary percutaneous coronary intervention (PCI). Reperfusion time may be affected by both intra-and extrahospital factors. The study attempted to identify factors affecting reperfusion time to reduce mortality and morbidity. Materials and Methods: In this cross-sectional study, 95 patients with chest pain who were admitted to a hospital emergency in Tehran (capital city of Iran) were admitted and those who were diagnosed with ST-segment Elevation myocardial infarction (STEMI) were candidates for primary PCI. Basic information was asked from the patients or companion of them. In addition, the PCI time recorded in the patient file was entered in the checklist. Results: The mean interval between the onset of symptoms and primary PCI was 218. 6± 21. 69 min. The interval between the first medical contact (FMC) and primary PCI was determined to be 87. 122± 183. 66 minutes. The mean time of door to balloon in the hospital was 42. 49± 78. 53 min. In addition, the mean time interval from symptom onset to FMC was 19. 47± 11. 84 minutes. In 31 cases (32. 6%), the emergency service (EMS) contacted. Three factors were identified to be associated with a delay between the onset of symptoms to primary PCI (or delay reperfusion time) including the previous history of myocardial infarction (MI) (p=0. 034), the severity of coronary artery disease, based on angiography (p=0. 043) and the type of vehicle used to transfer the patient to the hospital (p=0. 007). Conclusion: The reperfusion delay seems to be higher in our treatment center than in other centers. Three preceding factors of MI, the severity of coronary artery disease and the transmission of patients via EMS are considered factors associated with the reduction of reperfusion delay.

Introduction: This study aimed to evaluate the in-hospital mortality of patients with ST-segment Elevation myocardial infarction (STEMI), according to gender and other likely risk factors. Methods: This study reports on data relating to 1, 484 consecutive patients with STEMI registered from June 2016 to May 2018 in the Western Iran STEMI Registry. Data were collected using a standardized case report developed by the European Observational Registry Program (EORP). The relationship between in-hospital mortality and potential predicting variables was assessed multivariable logistic regression. Differences between groups in mortality rates were compared using chi-square tests and independent t-tests. Results: Out of the 1484 patients, 311(21%) were female. Women were different from men in terms of age (65. 8 vs. 59), prevalence of hypertension (HTN) (63. 7% vs. 35. 4%), diabetes mellitus (DM) (37. 7% vs. 16. 2%), hypercholesterolemia (36. 7% vs. 18. 5%) and the history of previous congestive heart failure (CHF) (6. 6% vs. 3. 0%). Smoking was more prevalent among men (55. 9% vs. 13. 2%). Although the in-hospital mortality rate was higher in women (11. 6% vs. 5. 5%), after adjusting for other risk factors, female sex was not an independent predictor for in-hospital mortality. Multivariable analysis identified that age and higher Killip class (≥ II) were significantly associated with in-hospital mortality rate. Conclusion: In-hospital mortality after STEMI in women was higher than men. However, the role of sex as an independent predictor of mortality disappeared in regression analysis. The gender based difference in in-hospital mortality after STEMI may be related to the poorer cardiovascular disease (CVD) risk factor profile of the women.